B1 (Thiamine / Benfotiamine): Helps nerves turn glucose into energy. Benfotiamine (a fat-soluble form) is especially protective against oxidative stress and glycation damage in diabetic neuropathy.

B3 (Niacinamide): Reduces neuroinflammation, improves nerve cell survival and repair, reduces oxidative stress, a process often involved with Neuropathy. Promotes Myelin repair, the insulating sheath surrounding nerves Improves blood flow by causing vasodilation. Better circulation supports nutrient and oxygen delivery to nerve cells

B5 (Pantothenic acid): Helps maintain proper nerve signaling and muscle control which can be impaired with neuropathy

B6 (Pyridoxine): Important for neurotransmitter production. Too little causes nerve damage; too much can also cause neuropathy, so dose matters.

B7 (Biotin): Helps with energy production necessary for nerve function 

B8 (Inositol): Precursor to essential components of nerve cell membrane and transmission signaling pathways and improves nerve conduction velocity. Helps to regulate overstimulation damage of nerves

B9 (folate): Helps with methylation processes and works with B12 in nerve repair.

B12 (Methylcobalamin): Essential for myelin sheath formation (the protective covering around nerves). Deficiency is one of the most common causes of neuropathy.

Effect: Together, they provide the “raw materials” for nerve repair and proper signal transmission.

A strong antioxidant that reduces oxidative stress around nerves.

Improves blood flow and glucose utilization, which is especially helpful in diabetic neuropathy.

Effect: Can decrease burning, pain, and numbness by reducing inflammation and free radical damage.

Supports energy production inside nerve cells’ mitochondria.

May stimulate nerve regeneration and reduce pain.

Effect: Boosts nerve healing and decreases discomfort.

Reduces inflammation that can irritate nerves

Regulates pain signaling and nerve sensitivity and provides chronic pain relief

Protects against further nerve damage

Helps with nerve regeneration and recovery after injury

An essential nutrient that helps maintain nerve signal transmission, particularly with a mixed neuropathy (sensory, motor and autonomic)

Supports membrane repair and myelin sheath integrity 

Contributes to nerve insulation and conduction speed and is a part of the nerve-protective methylation cycle

Boswellia serrata (Indian frankincense) is an herbal extract that’s been studied mainly for its anti-inflammatory and analgesic (pain-relieving) effects, which can be relevant in neuropathy. Here’s how it may work:

• Inhibition of Pro-Inflammatory Pathways

Boswellic acids, the active compounds, inhibit 5-lipoxygenase (5-LOX), an enzyme that drives production of leukotrienes (potent inflammatory mediators).

This reduces inflammation around nerves, which can help with nerve irritation and pain in conditions like diabetic neuropathy or inflammatory neuropathies.

• Reduction of Oxidative Stress

Neuropathy often involves oxidative damage to nerves.

Boswellia shows antioxidant activity, which helps protect nerve cells from free radical–induced injury.

• Neuroprotective Effects

Preclinical studies suggest boswellic acids may protect neurons by reducing glutamate excitotoxicity(overstimulation that can damage nerves).

Some evidence indicates it may help maintain myelin sheath integrity, which is often impaired in neuropathy.

• Pain Modulation

Boswellia may influence TRPV1 receptors and other pain pathways involved in neuropathic pain perception.

Animal studies have shown improvements in mechanical allodynia (pain from light touch) and thermal hyperalgesia (increased pain from heat).

• Potential Microcirculation Support

Some extracts may improve blood flow and reduce edema, which can help nerves function better, especially in diabetic neuropathy where circulation is compromised.

Antioxidant effect: ALA, B1, and others reduce oxidative damage that worsens nerve injury.

Repair & protection: B12 and folate rebuild myelin and DNA in nerve cells.

Energy support: B1, Acetyl-L-carnitine, and B vitamins improve mitochondrial function.

Inflammation control: antioxidants calm nerve irritation.

In short: Neuro-Blast work by protecting nerves from further injury, reducing oxidative stress, and providing the nutrients needed for nerve repair and signal transmission.